Medical Uses of Aromasin (Exemestane):
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Breast Cancer Treatment:
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Adjuvant Therapy: Exemestane is commonly prescribed to postmenopausal women with hormone-receptor-positive breast cancer after surgery and other treatments. It is used to reduce the risk of cancer recurrence by lowering estrogen levels.
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Metastatic Breast Cancer: Aromasin may also be used to treat metastatic (spreading) breast cancer in postmenopausal women whose cancer is hormone-receptor-positive and has not responded to other treatments.
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Prevention of Breast Cancer (In some cases): In high-risk postmenopausal women, Aromasin may be used as a preventive treatment to reduce the risk of developing breast cancer.
Mechanism of Action:
Aromasin (Exemestane) works by inhibiting aromatase, an enzyme that is involved in converting androgens (like testosterone) into estrogen. In postmenopausal women, most estrogen is produced through this conversion process, and by blocking this enzyme, Aromasin significantly reduces estrogen levels in the body.
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Lowering estrogen is effective in treating hormone-sensitive (estrogen receptor-positive) breast cancer, as many breast cancers grow in response to estrogen.
Dosage:
The typical dosage of Aromasin is 25 mg taken once daily, usually after a meal. However, the dosage can vary based on individual needs and the specific condition being treated. It is generally prescribed for a period of 5 years for adjuvant therapy in breast cancer.
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